Our new Crystal clear+ tissue clearing technique is the only method that delipidates samples with no alter in morphology and with minimal impact on structural integrity.
Megatome can be a vibrating microtome created to area a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform area profile, and minimal tissue harm and information loss.
Antibodies may take weeks to diffuse through only a few millimeters of tissue, with a steep labeling gradient from surface to core.
Megatome is designed for precision: the blade vibrates at the next frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Management mechanism.
SE takes advantage of a rotational electric powered subject to disperse hugely electromobile molecules (including antibodies or surfactant micelles) all through a porous sample with out damaging electrically billed constructions inside the tissue. This enables 2-four working day clearing of intact organs,
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Megatome is a novel microtome that enables for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue destruction and data loss.
eFLASH is often a speedy tissue labeling method that allows for uniform total-organ staining in 20 rounds of labeling.
The SmartSPIM mild sheet microscope presents unparalleled resolution and acquisition pace throughout intact tissue volumes, even though its modular design megatomi.com lets you upgrade and personalize person parts.
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Leverage the Apparent+ tissue clearing technique, as well as eFLASH and patented stochastic electrotransport systems, to fast distinct and label entire organs. Essential highlights and options include:
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